Opportunity Information: Apply for CDC RFA GH18 1808
This grant opportunity (CDC RFA GH18-1808) is a PEPFAR-funded cooperative agreement from the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), focused on strengthening Ethiopia's national response to HIV/AIDS by improving three closely linked areas: laboratory systems, strategic information, and technical leadership in public health. The overall intent is to build on prior HIV and tuberculosis (TB) laboratory strengthening work and address remaining gaps in Ethiopia's HIV/TB laboratory network and in the surveys and surveillance systems used to guide national programs. By improving both the evidence base (through better data and surveillance) and the diagnostic backbone (through higher-quality, more accessible testing), the project is designed to support progress toward HIV epidemic control and align with the UNAIDS 90-90-90 targets.
A major emphasis of the opportunity is expanding and improving strategic information through population-based and facility-based survey and surveillance activities led by the Ethiopian Public Health Institute (EPHI). The goal is to help national and regional decision-makers understand where infections are occurring, which communities are most affected, and which interventions are working. The funding supports more targeted, evidence-driven HIV programming by focusing resources on high-impact geographic areas and priority population groups, rather than relying on broad approaches that may miss emerging hotspots. This includes strengthening routine data generation and the analytical capacity needed to translate surveillance results into practical program decisions.
Another central component is the development and use of more real-time surveillance approaches for case-finding and outbreak investigation. In practice, this means improving the ability of the public health system to detect and respond quickly to ongoing or newly emerging HIV transmission networks. The opportunity envisions surveillance systems and methods that can identify clusters or networks of transmission and then guide public health action, such as directing prevention services to people and communities at elevated risk. The underlying logic is that quicker detection and response can reduce onward transmission and help programs stay ahead of shifting epidemic patterns.
On the laboratory side, the opportunity prioritizes strengthening the national laboratory system to ensure quality-assured HIV and TB diagnostic testing, including viral load (VL) testing, which is essential for monitoring treatment effectiveness and achieving viral suppression. The grant is designed to reinforce EPHI's role as a national leader in laboratory capacity building, ensuring that improvements in laboratories keep pace with current HIV prevention, care, and treatment strategies. This includes standardization, quality management, and the technical oversight needed to maintain reliable testing performance across the network.
The NOFO also supports scaling up HIV and TB diagnostics through several practical interventions that improve access and turnaround time for results. It highlights routine use of dried blood spot (DBS) specimens, which are especially valuable in settings where transporting whole blood is difficult and where cold-chain capacity may be limited. It also calls for the introduction of point-of-care testing (POCT), which can bring diagnostic services closer to patients and reduce delays between testing and clinical action. In addition, it emphasizes implementing a robust specimen referral system, recognizing that even with improved testing platforms, systems often fail when samples cannot move efficiently from collection sites to testing laboratories and results cannot return promptly to clinicians and patients.
Capacity building is aimed not only at the national reference laboratory level but also at regional laboratories, with a focus on both technical competency and management capability. This reflects an understanding that sustaining diagnostic quality depends on leadership, supervision, workforce development, and operational systems such as quality assurance, supply chain coordination, equipment maintenance, and data management. Strengthening these elements is positioned as essential to supporting PEPFAR-supported programming in Ethiopia, because reliable diagnostics and surveillance are foundational for identifying people living with HIV, linking them to treatment, monitoring outcomes, and controlling TB co-infection.
From a funding and administrative perspective, the opportunity is categorized as discretionary funding and uses a cooperative agreement mechanism, which typically indicates substantial involvement by the CDC in collaboration, technical direction, and monitoring during implementation. The posted award ceiling is $3,200,000, with an expectation of one award. The funding opportunity was created on September 26, 2017, with an original application closing date of November 26, 2017 (applications due by 11:59 p.m. Eastern Time). The CFDA number is 93.067, and eligibility is listed as "Others" with further clarification referenced in the original eligibility text.
In summary, the grant is designed to help Ethiopia close key gaps that limit HIV epidemic control by strengthening EPHI-led surveillance and strategic information systems, improving real-time detection and response to transmission networks, and upgrading the quality, reach, and operational performance of HIV/TB laboratory services, including viral load testing. Together, these improvements are framed as critical contributions to reaching the 90-90-90 targets by ensuring that more people are accurately diagnosed, more are effectively treated, and more achieve viral suppression, while public health programs are guided by timely, high-quality data.Apply for CDC RFA GH18 1808
- The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Strengthening Capacity for Laboratory Systems, Strategic Information, and Technical Leadership in Public Health for the National HIV/AIDS Response in the Federal Democratic Republic of Ethiopia under the President's Emergency Plan for AIDS Relie" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on Sep 26, 2017.
- Applicants must submit their applications by Nov 26, 2017 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $3,200,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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