Opportunity Information: Apply for PAR 25 197
The opportunity titled "Limited Competition: NCATS Clinical and Translational Science Award (CTSA) Program Research Education Grants Programs (R25 - Clinical Trial Not Allowed)" is a National Institutes of Health (NIH) funding announcement that supports research education projects under the NIH Research Education Program (R25). It is administered within the scope of the National Center for Advancing Translational Sciences (NCATS) and is tied to the Clinical and Translational Science Award (CTSA) Program. The main purpose of this R25 mechanism is not to fund traditional research studies, but to fund structured education activities that strengthen and expand the biomedical, behavioral, and clinical research workforce. In practical terms, the program is designed to help institutions develop or enhance educational programs that prepare learners to participate effectively in research, especially in areas aligned with clinical and translational science.
This is a discretionary grant program in the health funding category (CFDA/Assistance Listing 93.350). The funding instrument is a grant, and the opportunity is described as a "limited competition," which typically means eligibility or applicant pool is restricted in some way (for example, to certain institutions, networks, or program participants), rather than being open to all applicants. Based on the provided eligibility field, the eligible applicant type listed is "Public and State controlled institutions of higher education." The announcement also clarifies important restrictions related to foreign involvement: non-U.S. (foreign) organizations are not eligible to apply as the applicant organization, and non-U.S. components of U.S. organizations are also not eligible to apply. However, foreign components are allowed as defined in the NIH Grants Policy Statement, meaning a U.S. applicant organization may include certain project elements or collaborations that meet NIH's definition of a foreign component, provided they are justified and compliant with NIH policy.
A key constraint of this specific R25 notice is that clinical trials are not allowed. That generally means the proposed activities cannot include conducting a study in which participants are prospectively assigned to an intervention to evaluate effects on biomedical or health-related outcomes. Applicants can still propose education, training-enhancement, curriculum development, mentoring structures, and related workforce-development activities, but they must design the program so that it does not cross into clinical trial activity as defined by NIH. In the context of CTSA-related education, that often points toward programs that build competencies in translational research methods, team science, regulatory science, biostatistics, data science, community-engaged research practices, implementation science, entrepreneurship/innovation, ethics, reproducibility, and other skills needed to move discoveries toward clinical impact, without actually running interventional clinical studies as part of the R25-funded work.
The opportunity number is PAR-25-197, and the announcement was created on 2024-12-09. The original closing date listed is 2027-05-28, indicating a multi-year window during which applications may be accepted according to the schedule and due dates specified in the full announcement. The source data provided does not list an award ceiling or the expected number of awards, so applicants would need to consult the full funding opportunity announcement for budget limits, project period expectations, and any specific caps, set-asides, or CTSA-linked constraints. Overall, the program is best understood as NIH support for education-focused infrastructure and programming that complements existing training pathways and helps ensure the U.S. research enterprise has a well-prepared workforce capable of meeting national biomedical and clinical research needs, specifically within the NCATS CTSA ecosystem and without supporting clinical trial execution.Apply for PAR 25 197
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition: NCATS Clinical and Translational Science Award (CTSA) Program Research Education Grants Programs (R25 - Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.350.
- This funding opportunity was created on 2024-12-09.
- Applicants must submit their applications by 2027-05-28.
- Eligible applicants include: Public and State controlled institutions of higher education.
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