Opportunity Information: Apply for CDC RFA JG 25 0050
The Centers for Disease Control and Prevention (CDC), through its Global Health Center and under the President's Emergency Plan for AIDS Relief (PEPFAR), is soliciting applications for a cooperative agreement focused on strengthening and modernizing Malawi's HIV health information systems. The opportunity, titled "Improving quality of care and health outcomes through innovative systems and technologies in Malawi under PEPFAR" (Funding Opportunity Number: CDC RFA JG 25 0050; CFDA: 93.067), is designed to build on prior progress in Malawi by improving the quality, security, and usability of HIV data across the entire health system, from individual facilities up through district and national levels, ultimately supporting better patient outcomes and more effective program management.
The program emphasis is on making Malawi's HIV health information systems more accurate, reliable, timely, and fit for decision-making. Key priorities include strengthening existing data systems rather than replacing them wholesale, improving data security using International Organization for Standardization (ISO) approaches, and maintaining and upgrading the underlying infrastructure that keeps these systems functioning. Another major focus is interoperability: ensuring that different digital health platforms can exchange information smoothly and securely, so that data are not trapped in separate silos. The work also supports core operational needs such as patient records management, routine program monitoring, and timely reporting required by the Ministry of Health (MOH) and PEPFAR.
Expected results from the funded activities include measurable improvements in data reliability and accuracy, stronger use of data for reporting and decision-making, and expanded use of a sustainable nationwide HIV health information system capable of producing both aggregate reporting and case-based surveillance outputs. The NOFO also targets governance and implementation improvements for the broader Malawi health information system (MaHIS), with an emphasis on MOH leadership and stewardship. Practical outcomes include better data exchange across systems and improved site-level client identification, including deduplication, which helps reduce double counting, improves continuity of care, and supports more credible national reporting and analysis.
The scope of work is intentionally broad and systems-oriented, covering both technology and the capacity needed to run it long-term. This includes building and maintaining associated hardware and infrastructure, strengthening MOH capacity to manage and support the systems, expanding user support services, and introducing new technologies that are sustainable in Malawi's context. Across all these elements, the overall goal is modernization of a government-owned, secure, integrated platform for data collection and management that can function at every level of the health system while directly enabling improved quality of care and health outcomes for people affected by HIV.
In terms of funding and logistics, CDC anticipates approximately $7,000,000 in total funding for Year 1, contingent on the availability of funds. The posting notes that the "Award Ceiling for Year 1" is listed as $0 (none), which typically indicates that a specific per-award cap is not being set in the notice even though total available funding is estimated. CDC expects to make two awards. The instrument type is a cooperative agreement, meaning CDC anticipates substantial involvement in the implementation and oversight of the work compared with a standard grant. The original application closing date is February 21, 2025, and the opportunity was created on December 5, 2024.
Eligibility is wide and includes US and other governmental entities and a broad range of organizations: state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses. The awarding agency is listed as Centers for Disease Control - GHC, and the opportunity category is discretionary funding within the health activity category.Apply for CDC RFA JG 25 0050
- The Centers for Disease Control-GHC in the health sector is offering a public funding opportunity titled "Improving quality of care and health outcomes through innovative systems and technologies in Malawi under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on 2024-12-05.
- Applicants must submit their applications by 2025-02-21. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Unrestricted.
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Frequently Asked Questions (FAQs)
1) What is the name of this funding opportunity?
The opportunity is titled "Improving quality of care and health outcomes through innovative systems and technologies in Malawi under PEPFAR."
2) Who is offering this grant opportunity?
The awarding agency is the Centers for Disease Control and Prevention (CDC), through its Global Health Center (GHC), under the President's Emergency Plan for AIDS Relief (PEPFAR).
3) What is the Funding Opportunity Number (FON) and CFDA number?
Funding Opportunity Number: CDC RFA JG 25 0050. CFDA: 93.067.
4) What type of award is this?
This opportunity uses a cooperative agreement instrument, which means CDC anticipates substantial involvement in implementation and oversight compared with a standard grant.
5) What is the main purpose of the cooperative agreement?
The main purpose is to strengthen and modernize Malawi's HIV health information systems so HIV data are more accurate, reliable, timely, secure, and usable for decision-making across facility, district, and national levels, ultimately supporting better patient outcomes and stronger program management.
6) What country and program area does this work focus on?
The work focuses on Malawi and is centered on HIV health information systems in support of PEPFAR and Ministry of Health (MOH) needs.
7) What are the key priorities described in the notice?
Key priorities include strengthening existing systems rather than replacing them, improving data security using International Organization for Standardization (ISO) approaches, maintaining and upgrading underlying infrastructure, and improving interoperability so digital health platforms can exchange information smoothly and securely.
8) Does the opportunity focus on replacing Malawi's existing data systems?
No. A stated priority is strengthening existing data systems rather than replacing them wholesale.
9) What does "interoperability" mean in the context of this opportunity?
Interoperability refers to different digital health platforms being able to exchange information smoothly and securely, reducing data silos and supporting system-wide reporting and analysis.
10) What kinds of results are expected from funded activities?
Expected results include measurable improvements in data reliability and accuracy; stronger use of data for reporting and decision-making; and expanded use of a sustainable nationwide HIV health information system capable of producing both aggregate reporting and case-based surveillance outputs.
11) How does this opportunity support quality of care and health outcomes?
By improving the quality, security, and usability of HIV data, the initiative supports more credible reporting and analysis, better continuity of care (including improved client identification and deduplication), and more effective program management and decision-making that can translate into improved health outcomes.
12) What is MaHIS, and how is it referenced in this opportunity?
The notice references governance and implementation improvements for the broader Malawi health information system (MaHIS), emphasizing MOH leadership and stewardship.
13) What role does Malawi's Ministry of Health (MOH) play in this work?
The opportunity emphasizes MOH leadership and stewardship and includes strengthening MOH capacity to manage and support the systems over the long term.
14) What operational needs does this opportunity support?
It supports core operational needs such as patient records management, routine program monitoring, and timely reporting required by MOH and PEPFAR.
15) What is meant by improving site-level client identification and deduplication?
It refers to improving how clients are identified at the facility/site level and reducing duplicate records or double counting. This supports continuity of care and strengthens the credibility of national reporting and analysis.
16) What kinds of activities are included in the scope of work?
The scope is broad and systems-oriented, covering technology and long-term capacity. Activities described include maintaining and upgrading hardware and infrastructure, strengthening MOH capacity to manage and support systems, expanding user support services, and introducing sustainable new technologies appropriate to Malawi's context.
17) Is the goal to create a government-owned platform?
Yes. The overall goal is modernization of a government-owned, secure, integrated platform for data collection and management that can function at every level of the health system.
18) How much funding is anticipated for Year 1?
CDC anticipates approximately $7,000,000 in total funding for Year 1, contingent on the availability of funds.
19) What does it mean that the "Award Ceiling for Year 1" is listed as $0 (none)?
The posting notes an award ceiling of $0 (none), which typically indicates a specific per-award cap is not being set in the notice, even though total Year 1 funding is estimated.
20) How many awards does CDC expect to make?
CDC expects to make two awards.
21) When is the application closing date?
The original application closing date is February 21, 2025.
22) When was this opportunity created?
The opportunity was created on December 5, 2024.
23) What is the opportunity category and activity area?
The opportunity category is discretionary funding, and the activity category is health.
24) Who is eligible to apply?
Eligibility is broad and includes US and other governmental entities and many organization types, including: state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses.
25) Are for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) are listed as eligible, and small businesses are also listed separately as eligible.
26) Are nonprofits required to have 501(c)(3) status to be eligible?
No. The eligibility list includes nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status.
27) Are tribal governments and tribal organizations eligible?
Yes. Federally recognized tribal governments and other tribal organizations are included in the eligibility list.
28) Are universities and colleges eligible to apply?
Yes. Public and state-controlled institutions of higher education, as well as private institutions of higher education, are included as eligible applicants.
29) What does CDC mean by improving data security using ISO approaches?
The notice highlights improving data security using International Organization for Standardization (ISO) approaches, indicating a focus on structured, standards-based security practices for protecting data.
30) What levels of the health system are intended to benefit from this work?
The effort is intended to support the entire health system, from individual facilities to district and national levels, enabling both local use of data and national program reporting and surveillance outputs.
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