Opportunity Information: Apply for RFA TR 23 011
Emergency Awards: HEAL Initiative - New Innovator Award (DP2 Clinical Trial Not Allowed) is a National Institutes of Health (NIH) funding opportunity issued by the National Center for Advancing Translational Sciences (NCATS) in direct response to the ongoing nationwide public health emergency related to the opioid crisis, as declared and renewed by the U.S. Department of Health and Human Services. The opportunity is part of the Helping End Addiction Long-Term (HEAL) Initiative and is designed to accelerate highly innovative biomedical research that can meaningfully move the field forward on urgent problems tied to pain, opioid use disorder (OUD), and overdose (OD). The intent is to support bold, potentially high-impact ideas that might not fit neatly into traditional funding mechanisms but could reshape scientific thinking, challenge existing paradigms, or open up entirely new directions for addressing addiction and pain-related challenges.
This award specifically targets exceptionally creative postdoctoral researchers and newly independent Early Stage Investigators (ESIs). In practical terms, it is meant for researchers at the beginning of their independent careers (or on the cusp of independence) who have compelling, original concepts and the ability to execute them. The emphasis is on novelty and insight: proposals are expected to be more than incremental improvements and instead present innovative research concepts with the potential for major impact on broad and important biomedical problems within the HEAL mission space. Applications are encouraged to bring together unexpected combinations of disciplines, introduce new scientific directions, or apply novel methodologies that could yield transformative advances. As indicated in the title, clinical trials are not allowed under this FOA, so projects must be structured accordingly (for example, focusing on preclinical studies, mechanistic work, translational research that does not meet the definition of a clinical trial, data science approaches, platform development, or other non-trial human research that complies with NIH definitions and rules).
The funding opportunity is offered as a discretionary grant under the NIH DP2 New Innovator-style mechanism, with an award ceiling listed at $1,500,000. While the listing does not specify the exact number of anticipated awards, the structure and framing make clear that the program is selective and aimed at supporting a limited set of highly promising investigators pursuing unusually innovative ideas. The original application closing date for the referenced cycle was May 22, 2023, and the opportunity was created on April 19, 2023.
Eligibility is broad across a wide range of U.S.-based organizations and entity types. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; and small businesses. The FOA also explicitly highlights additional eligible applicant categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.
At the same time, there are clear restrictions related to foreign participation. Non-domestic (non-U.S.) entities or foreign institutions are not eligible to apply, and non-domestic components of U.S. organizations are not eligible. In addition, foreign components, as defined by the NIH Grants Policy Statement, are not allowed. These restrictions mean the applicant organization and project activities must be structured to remain fully domestic under NIH policy, without foreign components or foreign institutional involvement that would meet NIH's definition of a foreign component.
In summary, this FOA is a HEAL Initiative emergency-response funding opportunity from NIH/NCATS meant to quickly enable early career scientific leaders to pursue unconventional, high-impact, non-clinical-trial research aimed at addressing pain, OUD, and overdose. It prioritizes originality, cross-disciplinary convergence, and methodological innovation, while allowing applications from a wide spectrum of U.S. organizations and explicitly excluding foreign entities and foreign components.Apply for RFA TR 23 011
- The National Institutes of Health in the education, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Emergency Awards: HEAL Initiative- New Innovator Award (DP2 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213, 93.273, 93.350, 93.393, 93.395, 93.846, 93.847, 93.853, 93.865, 93.866.
- This funding opportunity was created on 2023-04-19.
- Applicants must submit their applications by 2023-05-22. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Browse more opportunities from the same category: Education, Food and Nutrition, Health, Income Security and Social Services
Next opportunity: FY2023 ABPP - Battlefield Interpretation Grant
Previous opportunity: Impacts of climate change across the cancer control continuum (R01 Clinical Trial Optional)
Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA TR 23 011
Applicants also applied for:
Applicants who have applied for this opportunity (RFA TR 23 011) also looked into and applied for these:
| Funding Opportunity |
|---|
| HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional) Apply for RFA NS 23 028 Funding Number: RFA NS 23 028 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $1,500,000 |
| HEAL Initiative: HEAL KIDS (Knowledge, Innovation and Discovery Studies) Pain: Acute Pain Clinical Trials Program (U01 Clinical Trial Required) Apply for RFA HD 24 011 Funding Number: RFA HD 24 011 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) Apply for RFA NS 24 019 Funding Number: RFA NS 24 019 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) Apply for PAR 24 075 Funding Number: PAR 24 075 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required) Apply for PAR 24 076 Funding Number: PAR 24 076 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed) Apply for RFA NS 25 012 Funding Number: RFA NS 25 012 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $350,000 |
| Advancing HIV service delivery through pharmacies and pharmacists (R01 Clinical Trial Optional) Apply for RFA MH 25 185 Funding Number: RFA MH 25 185 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH HEAL Initiative PainCare Clinician Training Program (PCTP): Mentored Clinical Scientist Development Awards (K08 - Clinical Trials Required) Apply for PAR 24 217 Funding Number: PAR 24 217 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Time-Sensitive Obesity Policy and Program Evaluation (R01) Apply for PAR 15 346 Funding Number: PAR 15 346 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed) Apply for RFA NS 25 023 Funding Number: RFA NS 25 023 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $350,000 |
| Time-Sensitive Evaluation of Policies Affecting Health Behaviors and Chronic Disease Risk (R01-Clinical Trial Not Allowed) Apply for PAR 25 312 Funding Number: PAR 25 312 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Inside Our Applicants Portal
Access Applicants Portal
- Grants Repository - Access current and historic funding opportunities with ease. Thousands of funding opportunities are published every week. We can help you sort through the database and find the eligible ones to apply for.
- Applicant Video Guides - The grant application process can be challenging to follow. We can help you with intuitive video guides to speed up the process and eliminate errors in submissions.
- Grant Proposal Wizard - We have developed a network of private funding organizations and investors across the United States. We can reach out and submit your proposal to these contacts to maximize your chances of getting the funding you need.
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Learn More
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA TR 23 011", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.